OrthoDB v9.1: cataloging evolutionary and functional annotations for animal, fungal, plant, archaeal, bacterial and viral orthologs.

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_94419F2D988E
Type
Article: article from journal or magazin.
Collection
Publications
Title
OrthoDB v9.1: cataloging evolutionary and functional annotations for animal, fungal, plant, archaeal, bacterial and viral orthologs.
Journal
Nucleic Acids Research
Author(s)
Zdobnov E.M., Tegenfeldt F., Kuznetsov D., Waterhouse R.M., Simão F.A., Ioannidis P., Seppey M., Loetscher A., Kriventseva E.V.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Publication state
Published
Issued date
2017
Peer-reviewed
Oui
Volume
45
Number
D1
Pages
D744-D749
Language
english
Abstract
OrthoDB is a comprehensive catalog of orthologs, genes inherited by extant species from a single gene in their last common ancestor. In 2016 OrthoDB reached its 9th release, growing to over 22 million genes from over 5000 species, now adding plants, archaea and viruses. In this update we focused on usability of this fast-growing wealth of data: updating the user and programmatic interfaces to browse and query the data, and further enhancing the already extensive integration of available gene functional annotations. Collating functional annotations from over 100 resources, and enabled us to propose descriptive titles for 87% of ortholog groups. Additionally, OrthoDB continues to provide computed evolutionary annotations and to allow user queries by sequence homology. The OrthoDB resource now enables users to generate publication-quality comparative genomics charts, as well as to upload, analyze and interactively explore their own private data. OrthoDB is available from http://orthodb.org.

Keywords
Algorithms, Animals, Archaea/genetics, Bacteria/genetics, Computational Biology/methods, Databases, Genetic, Evolution, Molecular, Fungi/genetics, Genomics/methods, Molecular Sequence Annotation, Plants/genetics, Software, User-Computer Interface, Viruses/genetics, Web Browser
Pubmed
Web of science
Open Access
Yes
Create date
20/09/2017 9:44
Last modification date
20/08/2019 15:56
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