Evaluation of the potential use of trabecular bone score to complement bone mineral density in the diagnosis of osteoporosis: a preliminary spine BMD-matched, case-control study.

Details

Serval ID
serval:BIB_91F1AD9753A7
Type
Article: article from journal or magazin.
Collection
Publications
Title
Evaluation of the potential use of trabecular bone score to complement bone mineral density in the diagnosis of osteoporosis: a preliminary spine BMD-matched, case-control study.
Journal
Journal of Clinical Densitometry
Author(s)
Pothuaud L., Barthe N., Krieg M.A., Mehsen N., Carceller P., Hans D.
ISSN
1094-6950
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
12
Number
2
Pages
170-176
Language
english
Notes
Publication types: Journal Article ; Multicenter Study
Publication Status: ppublish
Abstract
The trabecular bone score (TBS) is a new parameter that is determined from gray-level analysis of dual-energy X-ray absorptiometry (DXA) images. It relies on the mean thickness and volume fraction of trabecular bone microarchitecture. This was a preliminary case-control study to evaluate the potential diagnostic value of TBS as a complement to bone mineral density (BMD), by comparing postmenopausal women with and without fractures. The sample consisted of 45 women with osteoporotic fractures (5 hip fractures, 20 vertebral fractures, and 20 other types of fracture) and 155 women without a fracture. Stratification was performed, taking into account each type of fracture (except hip), and women with and without fractures were matched for age and spine BMD. BMD and TBS were measured at the total spine. TBS measured at the total spine revealed a significant difference between the fracture and age- and spine BMD-matched nonfracture group, when considering all types of fractures and vertebral fractures. In these cases, the diagnostic value of the combination of BMD and TBS likely will be higher compared with that of BMD alone. TBS, as evaluated from standard DXA scans directly, potentially complements BMD in the detection of osteoporotic fractures. Prospective studies are necessary to fully evaluate the potential role of TBS as a complementary risk factor for fracture.
Keywords
Absorptiometry, Photon, Aged, Bone Density, Bone and Bones/radiography, Bone and Bones/ultrastructure, Case-Control Studies, Female, Humans, Osteoporosis/radiography, Postmenopause, ROC Curve, Spinal Fractures/radiography, Statistics, Nonparametric
Pubmed
Web of science
Create date
11/02/2010 12:32
Last modification date
03/03/2018 19:30
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