Standards of care and novel approaches in the management of glioblastoma multiforme.

Details

Serval ID
serval:BIB_91ECCD1F2687
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Standards of care and novel approaches in the management of glioblastoma multiforme.
Journal
Chinese journal of cancer
Author(s)
Hottinger A.F., Stupp R., Homicsko K.
ISSN
1000-467X (Print)
ISSN-L
1944-446X
Publication state
Published
Issued date
01/2014
Peer-reviewed
Oui
Volume
33
Number
1
Pages
32-39
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Standard therapeutic approaches provide modest improvement in the progression-free and overall survival, necessitating the investigation of novel therapies. We review the standard treatment options for GBM and evaluate the results obtained in clinical trials for promising novel approaches, including the inhibition of angiogenesis, targeted approaches against molecular pathways, immunotherapies, and local treatment with low voltage electric fields.
Keywords
Adult, Angiogenesis Inhibitors/therapeutic use, Antibodies, Monoclonal, Humanized/therapeutic use, Bevacizumab, Brain Neoplasms/therapy, Cancer Vaccines/therapeutic use, Electric Stimulation Therapy, ErbB Receptors/antagonists & inhibitors, Gefitinib, Glioblastoma/therapy, Humans, Immunotherapy, Quinazolines/therapeutic use, Snake Venoms/therapeutic use, Standard of Care, Vaccines, Subunit/therapeutic use
Pubmed
Web of science
Open Access
Yes
Create date
02/06/2022 9:52
Last modification date
03/06/2022 6:37
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