Abnormal activation in the visual cortex after corneal refractive surgery for myopia: demonstration by functional magnetic resonance imaging.
Details
Serval ID
serval:BIB_8FC2937B726A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Abnormal activation in the visual cortex after corneal refractive surgery for myopia: demonstration by functional magnetic resonance imaging.
Journal
Ophthalmology
ISSN
0161-6420 (Print)
ISSN-L
0161-6420
Publication state
Published
Issued date
2001
Peer-reviewed
Oui
Volume
108
Number
12
Pages
2213-2218
Language
english
Notes
Publication types: Case Reports ; Journal ArticlePublication Status: ppublish. PDF type: Orginal research article
Abstract
OBJECTIVE: To try to correlate subjective photophobic symptoms with visual pathway modifications (from the retinal image to the visual cortex) after refractive surgery by exploring brain activation on photic stimulation.
DESIGN: Noncomparative case series.
PARTICIPANTS: Four subjects reporting discomfort produced by luminance (glare, halos, starbursts, or a combination thereof) in one eye after laser in situ keratomileusis (LASIK) were enrolled. The contralateral myopic eye (control) had no visual impairment and had undergone LASIK without complications or had not had previous surgery.
METHODS: Functional magnetic resonance imaging was performed during photic stimulation, delivered by an optical fiber, of the affected and unaffected eyes.
RESULTS: Functional magnetic resonance imaging provided evidence that most subjective visual symptoms correlated with anatomic flap abnormalities are associated with a higher signal increase in the visual association cortices compared with a nonsymptomatic eye.
CONCLUSIONS: Functional magnetic resonance imaging of the visual cortex may help in exploring the mechanisms involved in glare effects after refractive surgery.
DESIGN: Noncomparative case series.
PARTICIPANTS: Four subjects reporting discomfort produced by luminance (glare, halos, starbursts, or a combination thereof) in one eye after laser in situ keratomileusis (LASIK) were enrolled. The contralateral myopic eye (control) had no visual impairment and had undergone LASIK without complications or had not had previous surgery.
METHODS: Functional magnetic resonance imaging was performed during photic stimulation, delivered by an optical fiber, of the affected and unaffected eyes.
RESULTS: Functional magnetic resonance imaging provided evidence that most subjective visual symptoms correlated with anatomic flap abnormalities are associated with a higher signal increase in the visual association cortices compared with a nonsymptomatic eye.
CONCLUSIONS: Functional magnetic resonance imaging of the visual cortex may help in exploring the mechanisms involved in glare effects after refractive surgery.
Keywords
Adult, Cornea/surgery, Female, Humans, Keratomileusis, Laser In Situ/adverse effects, Magnetic Resonance Imaging, Male, Middle Aged, Myopia/surgery, Photophobia/diagnosis, Photophobia/etiology, Retina/physiopathology, Visual Cortex/pathology, Visual Cortex/physiopathology, Visual Pathways/physiopathology
Pubmed
Web of science
Create date
24/03/2013 17:28
Last modification date
20/08/2019 14:53
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