Paranasal sinus metastasis of breast cancer.

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State: Public
Version: author
Serval ID
serval:BIB_8E80A2AA005C
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Paranasal sinus metastasis of breast cancer.
Journal
BMJ Case Reports
Author(s)
Pittoni P., Di Lascio S., Conti-Beltraminelli M., Valli M.C., Espeli V., Bongiovanni M., Richetti A., Pagani O.
ISSN
1757-790X (Electronic)
Publication state
Published
Issued date
2014
Volume
2014
Pages
1-5
Language
english
Notes
Publication types: Journal Article Publication Status: epublishPDF: Case Report
Abstract
A 76-year-old woman presented with symptoms suggestive of acute sinusitis. Previously, her breast carcinoma was treated with right lumpectomy, adjuvant chemotherapy and breast radiotherapy. She remained free from recurrence for the following 8 years. After initial treatment with antibiotics, the local symptom worsened with exophthalmos, eye blindness and development of an ulceration of the hard palate. MRI showed irregular enhancement of the nasal cavity extended to the maxillary sinus and ethmoidal lamina and concomitant infiltration of the orbit and skull base. A biopsy of the palatal ulcer showed a poorly differentiated adenocarcinoma and was compared with the histology of the primary breast tumour and it was concluded for the same morphology. After discussion at the multidisciplinary team, a specific chemotherapy has been activated with an initial local response. Further surgical resection was not thought appropriate and the patient has subsequently undergone palliative radiotherapy to the right paranasal lesions to improve local disease control.
Pubmed
Create date
21/01/2015 10:19
Last modification date
20/08/2019 15:52
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