Detection of carotid adventitial vasa vasorum and plaque vascularization with ultrasound cadence contrast pulse sequencing technique and echo-contrast agent.
Details
Serval ID
serval:BIB_8E425A9FFDFC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Detection of carotid adventitial vasa vasorum and plaque vascularization with ultrasound cadence contrast pulse sequencing technique and echo-contrast agent.
Journal
Stroke; A Journal of Cerebral Circulation
ISSN
1524-4628 (Electronic)
ISSN-L
0039-2499
Publication state
Published
Issued date
2007
Volume
38
Number
10
Pages
2841-2843
Language
english
Notes
Publication types: Clinical Trial ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
BACKGROUND AND PURPOSE: Adventitial vasa vasorum and plaque vascularization have been established as predictors of unstable atheromasic lesions in cerebro- and cardiovascular patients. Ultrasound contrast agents provide reliable information on tissue perfusion and microcirculation. We used contrast ultrasound duplex scanning to identify carotid plaque vascularization.
METHODS: Contrast carotid duplex scanning was performed in 23 patients with plaques of different degree of stenosis and echogenicity.
RESULTS: Plaque vascularization was detected in the fibrous and fibro-fatty tissue and not observed in the calcific nor in the necrotic and hemorrhagic tissue. Constantly, a small vessel was observed under ulcerations.
CONCLUSIONS: Carotid contrast ultrasound imaging appears to be an emerging technique for identifying plaque angiogenesis. Further studies are needed to clarify the role of plaque angiogenesis for assessing cerebrovascular risk and to monitor effects of therapies aimed to plaque remodelling.
METHODS: Contrast carotid duplex scanning was performed in 23 patients with plaques of different degree of stenosis and echogenicity.
RESULTS: Plaque vascularization was detected in the fibrous and fibro-fatty tissue and not observed in the calcific nor in the necrotic and hemorrhagic tissue. Constantly, a small vessel was observed under ulcerations.
CONCLUSIONS: Carotid contrast ultrasound imaging appears to be an emerging technique for identifying plaque angiogenesis. Further studies are needed to clarify the role of plaque angiogenesis for assessing cerebrovascular risk and to monitor effects of therapies aimed to plaque remodelling.
Keywords
Aged, Calcinosis/pathology, Calcinosis/ultrasonography, Carotid Arteries/pathology, Carotid Arteries/ultrasonography, Carotid Stenosis/pathology, Carotid Stenosis/ultrasonography, Female, Humans, Male, Necrosis, Neovascularization, Pathologic/pathology, Neovascularization, Pathologic/ultrasonography, Severity of Illness Index, Ultrasonography, Doppler, Duplex/methods, Vasa Vasorum/pathology, Vasa Vasorum/ultrasonography
Pubmed
Web of science
Open Access
Yes
Create date
09/02/2015 12:02
Last modification date
20/08/2019 14:52
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