Chronotopic maps in human supplementary motor area.

Details

Ressource 1Download: 30897088_BIB_8E15FD0D1EA1.pdf (7268.25 [Ko])
State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_8E15FD0D1EA1
Type
Article: article from journal or magazin.
Collection
Publications
Title
Chronotopic maps in human supplementary motor area.
Journal
PLoS biology
Author(s)
Protopapa F., Hayashi M.J., Kulashekhar S., van der Zwaag W., Battistella G., Murray M.M., Kanai R., Bueti D.
ISSN
1545-7885 (Electronic)
ISSN-L
1544-9173
Publication state
Published
Issued date
03/2019
Peer-reviewed
Oui
Volume
17
Number
3
Pages
e3000026
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Time is a fundamental dimension of everyday experiences. We can unmistakably sense its passage and adjust our behavior accordingly. Despite its ubiquity, the neuronal mechanisms underlying the capacity to perceive time remains unclear. Here, in two experiments using ultrahigh-field 7-Tesla (7T) functional magnetic resonance imaging (fMRI), we show that in the medial premotor cortex (supplementary motor area [SMA]) of the human brain, neural units tuned to different durations are orderly mapped in contiguous portions of the cortical surface so as to form chronomaps. The response of each portion in a chronomap is enhanced by neighboring durations and suppressed by nonpreferred durations represented in distant portions of the map. These findings suggest duration-sensitive tuning as a possible neural mechanism underlying the recognition of time and demonstrate, for the first time, that the representation of an abstract feature such as time can be instantiated by a topographical arrangement of duration-sensitive neural populations.
Pubmed
Web of science
Open Access
Yes
Create date
15/04/2019 7:48
Last modification date
20/08/2019 14:52
Usage data