Sinonasal relapses of a primary isolated extranodal NK/T-cell lymphoma of the testis.

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Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_8D46568F4071
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Sinonasal relapses of a primary isolated extranodal NK/T-cell lymphoma of the testis.
Journal
BMJ case reports
Author(s)
Hallak B., Cairoli A., Bouayed S., Berthod G.
ISSN
1757-790X (Electronic)
ISSN-L
1757-790X
Publication state
Published
Issued date
13/08/2019
Peer-reviewed
Oui
Volume
12
Number
8
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: epublish
Abstract
WHO first recognised extranodal NK/T-cell lymphoma (ENKTCL) in 2001, thanks to technical advances in anatomopathology and immunohistochemistry. It is divided into nasal and extranasal subgroups depending on the primary site. Primary isolated NK/T-cell lymphoma of the testis is rare. Typical recurrence sites of primary testicular NK/T-cell lymphoma are the gastrointestinal tract, lymph nodes, skin, spleen and central nervous system. Nasal relapses of a primary NK/T-cell lymphoma of the testis are very rare and according to our knowledge, no other case has been reported yet in the literature. The authors report the case of a 35-year-old Caucasian man relapsing twice in the nasal cavity 1 year after initial diagnosis and treatment of a primary isolated, stage IE, ENKTCL of the testis. We report the clinical and radiological presentation of the nasal relapses and the different modalities of treatment that were applied. Sinonasal relapses of an isolated primary NK/T-cell lymphoma of the testis are very rare. ENKTCL is a very aggressive entity, even at an early stage, therefore, requiring a multimodal treatment approach including chemotherapy and radiotherapy. New strategies to treat this disease are needed.
Keywords
Adult, Combined Modality Therapy, Diagnosis, Differential, Humans, Lymphoma, Extranodal NK-T-Cell/diagnosis, Lymphoma, Extranodal NK-T-Cell/pathology, Lymphoma, Extranodal NK-T-Cell/therapy, Male, Neoplasm Metastasis, Neoplasm Recurrence, Local/diagnosis, Neoplasm Recurrence, Local/diagnostic imaging, Neoplasm Recurrence, Local/therapy, Nose Neoplasms/diagnosis, Nose Neoplasms/diagnostic imaging, Nose Neoplasms/secondary, Nose Neoplasms/therapy, Positron-Emission Tomography, Testicular Neoplasms/diagnosis, Testicular Neoplasms/pathology, Testicular Neoplasms/therapy, Tomography, X-Ray Computed, cancer - see oncology, ear, nose and throat, radiotherapy
Pubmed
Open Access
Yes
Create date
11/09/2019 16:31
Last modification date
30/04/2021 7:12
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