Doses aux organes à risque en radiothérapie conformationnelle et en radiothérapie stéréotaxique : les poumons [Lung dose constraints for normo-fractionated radiotherapy and for stereotactic body radiation therapy]

Details

Serval ID
serval:BIB_8C4518EC43DB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Doses aux organes à risque en radiothérapie conformationnelle et en radiothérapie stéréotaxique : les poumons [Lung dose constraints for normo-fractionated radiotherapy and for stereotactic body radiation therapy]
Journal
Cancer radiotherapie
Author(s)
Blais E., Pichon B., Mampuya A., Antoine M., Lagarde P., Kantor G., Breton-Callu C., Lefebvre C., Gerard M., Aamarcha A., Ozsahin M., Bourhis J., Maingon P., Troussier I., Pourel N.
ISSN
1769-6658 (Electronic)
ISSN-L
1278-3218
Publication state
Published
Issued date
10/2017
Peer-reviewed
Oui
Volume
21
Number
6-7
Pages
584-596
Language
french
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Radiation-induced lung disease (RILD) is common after radiation therapy and represents cornerstone toxicities after treatment of thoracic malignancies. From a review of literature, the objective of this article was to summarize clinical and non-clinical parameters associated with the risk of RILD in the settings of normo-fractionated radiotherapy and stereotactic body radiation therapy (SBRT). For the treatment of lung cancers with a normo-fractionated treatment, the mean lung dose (MLD) should be below 15-20Gy. For a thoracic SBRT, V20Gy<10% and MLD<6Gy are recommended. One should pay attention to central tumors and respect specific dose constraints to the bronchial tree. The recent technological improvements may represent an encouraging way to decrease lung toxicities. Finally, our team developed a calculator in order to predict the risk of radiation pneumonitis.

Keywords
Dose Fractionation, Humans, Lung/radiation effects, Lung Diseases/etiology, Lung Neoplasms/radiotherapy, Organs at Risk/radiation effects, Radiation Pneumonitis/etiology, Radiosurgery/methods, Thoracic Neoplasms/radiotherapy, Dose constraints, Doses de tolérance, Lung, Normo-fractionated radiotherapy, Organ at risk, Organe à risque, Poumons, Radiothérapie conformationnelle, Radiothérapie stéréotaxique, Stereotactic body radiation therapy
Pubmed
Web of science
Create date
28/09/2017 8:05
Last modification date
20/08/2019 14:50
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