Cytologic features of meningioma: An analysis of common and uncommon subtypes and diagnostic difficulties during intraoperative procedures.

Details

Serval ID
serval:BIB_8C35047E5929
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cytologic features of meningioma: An analysis of common and uncommon subtypes and diagnostic difficulties during intraoperative procedures.
Journal
Cytopathology
Author(s)
Rodríguez-García A.M., Esteban-Rodríguez I., Jiménez-Heffernan J.A., Bárcena C., López-Muñoz S., López-Ferrer P.
ISSN
1365-2303 (Electronic)
ISSN-L
0956-5507
Publication state
In Press
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Despite common histogenesis meningiomas have a wide morphologic spectrum, and the World Health Organization (WHO) recognizes 15 subtypes. They are the most common brain tumour in adults and typically have an extra-axial location. Although there have been important advances in the molecular biology of meningiomas its diagnosis is based on histopathologic features. The great majority are benign WHO grade 1 tumours. There are specific criteria for assigning WHO grade 2 and 3 that can be applied to all meningioma subtypes. Regardless of these criteria, chordoid and clear cell morphologic subtypes are considered grade 2. WHO grade 3 tumours exhibit a very high mitotic index, frank anaplasia or specific molecular abnormalities. The impressive morphologic diversity shown by meningiomas makes them a diagnostic challenge, which can be even greater in intraoperative studies. The focus of this article is to describe and illustrate their main cytologic features, with emphasis on the most infrequent subtypes.
Keywords
cytology, intraoperative cytology, meningioma
Pubmed
Web of science
Open Access
Yes
Create date
24/10/2023 13:31
Last modification date
25/11/2023 8:08
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