Tumoral Venous Invasion after Distal Pancreatectomy: A Risk Factor for Recurrence

Details

Serval ID
serval:BIB_8B01B93A61AD
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Tumoral Venous Invasion after Distal Pancreatectomy: A Risk Factor for Recurrence
Journal
Digestive Surgery
Author(s)
Joliat Gaëtan-Romain, Petermann David, Demartines Nicolas, Halkic Nermin, Schäfer Markus
ISSN
1421-9883
Publication state
Published
Issued date
2019
Peer-reviewed
Oui
Volume
36
Number
4
Pages
317-322
Language
english
Abstract
BACKGROUND: Few data exist on postoperative outcomes of patients with pancreatic body-tail malignancies and tumoral venous invasion (VI). This study aimed at comparing survival and recurrence rate (RR) after distal pancreatectomy for adenocarcinoma in patients with and without tumoral VI.
METHODS: All consecutive distal pancreatectomies (2000-2015) were collected. Demographics and peri- and postoperative data were recorded. Survivals were calculated using Kaplan-Meier curves.
RESULTS: A total of 45 patients underwent distal pancreatectomies for malignancies, of which 33 patients had ductal adenocarcinomas and 2 had cystadenocarcinomas. Among these 35 adenocarcinomas, histological VI was found in 28 patients (80%). Characteristics and intraoperative data of patients with and without VI were similar. Complication rates were 15 of 28 (54%) in the VI group and 3 of 7 (43%) in the group without VI (p = 0.612). Five-year survival for the group with and without VI were 19 and 39% (p = 0.232), respectively. RR was 16 of 28 (57%) for the VI group and 1 of 7 (14%) for the group without VI (p = 0.042).
CONCLUSION: VI did not have an effect on postoperative -complications. Survivals were similar in case of VI or not. On the contrary, RR was higher in the VI group.
Keywords
Adenocarcinoma, Aged, Carcinoma, Pancreatic Ductal, Distal pancreatectomy, Female, Humans, Male, Middle Aged, Neoplasm Invasiveness, Neoplasm Recurrence, Local, Pancreatectomy, Pancreatic Neoplasms, Pancreatic surgery, Postoperative Complications, Prospective Studies, Risk Factors, Survival Rate, Vascular invasion, Veins
Pubmed
Create date
11/02/2021 1:55
Last modification date
12/02/2021 7:25
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