Arterial dilatory reserve in congestive heart failure

Details

Serval ID
serval:BIB_8A87E82532FF
Type
Article: article from journal or magazin.
Collection
Publications
Title
Arterial dilatory reserve in congestive heart failure
Journal
Journal of Hypertension. Supplement
Author(s)
Zelis  R., Hayoz  D., Drexler  H., Munzel  T., Hornig  B., Zeiher  A. M., Just  H., Brunner  H. R.
ISSN
0952-1178 (Print)
Publication state
Published
Issued date
08/1992
Volume
10
Number
6
Pages
S65-7
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Aug
Abstract
AIM: The purpose of this study was to determine whether there are abnormalities in flow-mediated large vessel relaxation in patients with congestive heart failure (CHF). METHODS: The radial arterial diameter and flow responses upon the release of 10 min of forearm arterial occlusion (reactive hyperemia) were measured with ultrasound and Doppler devices. RESULTS: In patients with CHF there was a 26% reduction in peak blood flow (P = 0.09) compared to age-matched controls. However, the increase in arterial diameter that followed the peak blood flow was reduced by 49% in CHF (P < 0.01). CONCLUSIONS: The causes of the abnormal flow-mediated large artery relaxation in CHF are unclear; both structural and endothelial abnormalities may contribute.
Keywords
Blood Flow Velocity Case-Control Studies Forearm/blood supply Heart Failure, Congestive/*physiopathology Humans Ischemia Middle Aged Muscle Relaxation/physiology Muscle, Smooth, Vascular/physiology/physiopathology Radial Artery/anatomy & histology/*physiology/ultrasonography Regional Blood Flow/physiology
Pubmed
Web of science
Create date
17/01/2008 17:38
Last modification date
20/08/2019 15:49
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