Fetal cardiac cine magnetic resonance imaging in utero.

Details

Serval ID
serval:BIB_8A51E5777B9A
Type
Article: article from journal or magazin.
Collection
Publications
Title
Fetal cardiac cine magnetic resonance imaging in utero.
Journal
Scientific reports
Author(s)
Chaptinel J., Yerly J., Mivelaz Y., Prsa M., Alamo L., Vial Y., Berchier G., Rohner C., Gudinchet F., Stuber M.
ISSN
2045-2322 (Electronic)
ISSN-L
2045-2322
Publication state
Published
Issued date
14/11/2017
Peer-reviewed
Oui
Volume
7
Number
1
Pages
15540
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Fast magnetic resonance imaging (MRI) led to the emergence of 'cine MRI' techniques, which enable the visualization of the beating heart and the assessment of cardiac morphology and dynamics. However, established cine MRI methods are not suitable for fetal heart imaging in utero, where anatomical structures are considerably smaller and recording an electrocardiogram signal for synchronizing MRI data acquisition is difficult. Here we present a framework to overcome these challenges. We use methods for image acquisition and reconstruction that robustly produce images with sufficient spatial and temporal resolution to detect the heart contractions of the fetus, enabling a retrospective gating of the images and thus the generation of images of the beating heart. To underline the potential of our approach, we acquired in utero images in six pregnant patients and compared these with their echocardiograms. We found good agreement in terms of diameter and area measurements, and low inter- and intra- observer variability. These results establish MRI as a reliable modality for fetal cardiac imaging, with a substantial potential for prenatal evaluation of congenital heart defects.
Keywords
Cardiac Imaging Techniques/methods, Female, Fetal Heart/abnormalities, Fetal Heart/ultrastructure, Humans, Image Interpretation, Computer-Assisted/methods, Image Processing, Computer-Assisted/methods, Magnetic Resonance Imaging, Cine/methods, Pregnancy, Prenatal Diagnosis/methods, Reproducibility of Results
Pubmed
Web of science
Open Access
Yes
Create date
16/11/2017 21:14
Last modification date
20/08/2019 15:49
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