From radiobiology to technology: what is changing in radiotherapy for prostate cancer.

Details

Serval ID
serval:BIB_8A495E1A7F50
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
From radiobiology to technology: what is changing in radiotherapy for prostate cancer.
Journal
Expert Review of Anticancer Therapy
Author(s)
De Bari B., Fiorentino A., Arcangeli S., Franco P., D'Angelillo R.M., Alongi F.
ISSN
1744-8328 (Electronic)
ISSN-L
1473-7140
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
14
Number
5
Pages
553-564
Language
english
Notes
Publication types: Journal Article ; Review Publication Status: ppublish Publication type : Review
Abstract
In the last decades, new technologies have been introduced in the daily clinical practice of the radiation oncologist: 3D-Conformal radiotherapy (RT) became almost universally available, thereafter, intensity modulated RT (IMRT) gained large diffusion, due to its potential impact in improving the clinical outcomes, and more recently, helical and volumetric arc IMRT with image-guided RT are becoming more and more diffused and used for prostate cancer patients. The conventional dose-fractionation results to be the best compromise between the efficacy and the safety of the treatment, but combining new techniques, modern RT allows to overcame one of the major limits of the 'older' RT: the impossibility of delivering higher total doses and/or high dose/fraction. The evidences regarding radiobiology, clinical and technological evolution of RT in prostate cancer have been reported and discussed.
Keywords
Humans, Male, Prostatic Neoplasms/radiotherapy, Radiotherapy/methods
Pubmed
Web of science
Create date
20/01/2015 18:53
Last modification date
20/08/2019 14:49
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