Disadvantaged Early-Life Socioeconomic Circumstances Are Associated With Low Respiratory Function in Older Age.

Details

Serval ID
serval:BIB_89C8FA7F7EF7
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Disadvantaged Early-Life Socioeconomic Circumstances Are Associated With Low Respiratory Function in Older Age.
Journal
The journals of gerontology. Series A, Biological sciences and medical sciences
Author(s)
Cheval B., Chabert C., Orsholits D., Sieber S., Guessous I., Blane D., Kliegel M., Janssens J.P., Burton-Jeangros C., Pison C., Courvoisier D.S., Boisgontier M.P., Cullati S.
ISSN
1758-535X (Electronic)
ISSN-L
1079-5006
Publication state
Published
Issued date
18/06/2019
Peer-reviewed
Oui
Volume
74
Number
7
Pages
1134-1140
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Poor lung function in late life may stem from early-life risk factors, but the epidemiological evidence is inconsistent. We investigated whether individuals who experienced disadvantageous socioeconomic circumstances (SEC) in early life showed lower levels of respiratory function in older age, a steeper decline over time, and whether these relationships were explained by adult-life SEC, body mass index, and physical inactivity in older age.
We used data from the Survey of Health Ageing and Retirement in Europe (2004-2015). Participants' peak expiratory flow (PEF) was assessed with a mini-Wright peak flow meter at second, fourth, and sixth waves. Confounder-adjusted linear mixed-effect models were used to examine the associations between early-life SEC and PEF in older age. A total of 21,734 adults aged 50-96 years (46,264 observations) were included in the analyses.
Older adults with disadvantaged early-life SEC showed lower levels of PEF compared with those with advantaged early-life SEC. The association between early-life SEC and late-life PEF persisted after adjusting for adult-life SEC, smoking, physical inactivity, and body mass index. PEF declined with age, but the effect of early-life SEC on this decline was not consistent across robustness and sensitivity analyses.
Early life is a sensitive period for respiratory health. Further considering the effect of SEC arising during this period may improve the prevention of chronic respiratory diseases.
Keywords
Aged, Aged, 80 and over, Aging/physiology, Europe/epidemiology, Female, Geriatric Assessment/methods, Health Status Disparities, Health Surveys, Humans, Life History Traits, Male, Middle Aged, Respiratory Function Tests/methods, Respiratory Function Tests/statistics & numerical data, Risk Factors, Sedentary Behavior, Smoking/epidemiology, Socioeconomic Factors, Aging, Health status, Peak expiratory flow, Respiratory system, Socioeconomic factors
Pubmed
Web of science
Open Access
Yes
Create date
24/06/2019 17:25
Last modification date
27/04/2020 6:20
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