Anemia and chronic kidney disease are associated with poor outcomes in heart failure patients.

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Serval ID
serval:BIB_89AE09013B1C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Anemia and chronic kidney disease are associated with poor outcomes in heart failure patients.
Journal
BMC nephrology
Author(s)
Luthi J.C., Flanders W.D., Burnier M., Burnand B., McClellan W.M.
ISSN
1471-2369[electronic]
Publication state
Published
Issued date
2006
Volume
7
Pages
3
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: epublish
Abstract
BACKGROUND: Chronic kidney disease (CKD) has been linked to higher heart failure (HF) risk. Anemia is a common consequence of CKD, and recent evidence suggests that anemia is a risk factor for HF. The purpose of this study was to examine among patients with HF, the association between CKD, anemia and inhospital mortality and early readmission. METHODS: We performed a retrospective cohort study in two Swiss university hospitals. Subjects were selected based the presence of ICD-10 HF codes in 1999. We recorded demographic characteristics and risk factors for HF. CKD was defined as a serum creatinine > or = 124 956;mol/L for women and > or = 133 micromol/L for men. The main outcome measures were inhospital mortality and thirty-day readmissions. RESULTS: Among 955 eligible patients hospitalized with heart failure, 23.0% had CKD. Twenty percent and 6.1% of individuals with and without CKD, respectively, died at the hospital (p < 0.0001). Overall, after adjustment for other patient factors, creatinine and hemoglobin were associated with an increased risk of death at the hospital, and hemoglobin was related to early readmission. CONCLUSION: Both CKD and anemia are frequent among older patients with heart failure and are predictors of adverse outcomes, independent of other known risk factors for heart failure.
Keywords
Adolescent, Adult, Aged, Aged, 80 and over, Anemia, Cardiac Output, Low, Chronic Disease, Cohort Studies, Creatinine, Female, Hemoglobins, Hospital Mortality, Humans, Kidney Diseases, Male, Middle Aged, Multivariate Analysis, Patient Readmission, Prevalence, Retrospective Studies
Pubmed
Open Access
Yes
Create date
04/03/2008 14:58
Last modification date
20/08/2019 14:48
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