Determination of the effective dose delivered by image guided radiotherapy in head & neck and breast treatments.

Details

Serval ID
serval:BIB_892D1353C653
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Determination of the effective dose delivered by image guided radiotherapy in head & neck and breast treatments.
Journal
Zeitschrift fur medizinische Physik
Author(s)
Conrad M., Bolard G., Nowak M., De Bari B., Jeanneret-Sozzi W., Bourhis J., Germond J.F., Bochud F., Moeckli R.
ISSN
1876-4436 (Electronic)
ISSN-L
0939-3889
Publication state
Published
Issued date
12/2018
Peer-reviewed
Oui
Volume
28
Number
4
Pages
276-285
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Image guided radiotherapy (IGRT) improves patient positioning for treatment delivery at the cost of an additional dose. This work aimed to calculate the effective dose (as an indicator of dose) for head & neck (H&N) and breast IGRT treatments by implementing dose calculation models to determine the dose distributions.
The kV dose-models were created for the IGRT systems of Elekta Synergy (XVI) and Varian Clinac (OBI) linear accelerators within Philips Pinnacle TPS. Profiles and depth dose curves were measured in water. The models were validated in a CIRS thorax phantom. The IGRT dose distributions for five H&N and five breast patients were calculated. The effective dose was determined from the dose distributions following ICRP 103 recommendations. Moreover, time-saving approximations were studied in order to propose an alternative way of segmenting the tissues for a clinical implementation of the method.
The effective dose specifically associated with IGRT varied from 1 to 10mSv depending on the protocol. The kV dose-model allowed us to calculate the dose distributions from IGRT for different configurations and patients, and to determine effective dose for IGRT protocols. The clinical implementation of the method was found to reduce time and to introduce a small enough increase of uncertainty in the results to be clinically usable.
Keywords
Breast Neoplasms/radiotherapy, Female, Head and Neck Neoplasms/radiotherapy, Humans, Models, Theoretical, Radiotherapy Dosage, Radiotherapy, Image-Guided, Breast, Effective dose, Head and Neck, IGRT
Pubmed
Web of science
Create date
15/02/2018 20:51
Last modification date
20/08/2019 14:48
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