Diffantom: Whole-Brain Diffusion MRI Phantoms Derived from Real Datasets of the Human Connectome Project.

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Serval ID
serval:BIB_88F17372B09D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Diffantom: Whole-Brain Diffusion MRI Phantoms Derived from Real Datasets of the Human Connectome Project.
Journal
Frontiers In Neuroinformatics
Author(s)
Esteban O., Caruyer E., Daducci A., Bach-Cuadra M., Ledesma-Carbayo M.J., Santos A.
ISSN
1662-5196 (Electronic)
ISSN-L
1662-5196
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
10
Pages
4
Language
english
Abstract
Food allergies are believed to be on the rise and currently management relies on the avoidance of the food. Hen's egg allergy is after cow's milk allergy the most common food allergy; eggs are used in many food products and thus difficult to avoid. A technological process using a combination of enzymatic hydrolysis and heat treatment was designed to produce modified hen's egg with reduced allergenic potential. Biochemical (SDS-PAGE, Size exclusion chromatography and LC-MS/MS) and immunological (ELISA, immunoblot, RBL-assays, animal model) analysis showed a clear decrease in intact proteins as well as a strong decrease of allergenicity. In a clinical study, 22 of the 24 patients with a confirmed egg allergy who underwent a double blind food challenge with the hydrolysed egg remained completely free of symptoms. Hydrolysed egg products may be beneficial as low allergenic foods for egg allergic patients to extent their diet. This article is protected by copyright. All rights reserved.
Pubmed
Web of science
Open Access
Yes
Create date
16/02/2016 18:20
Last modification date
20/08/2019 15:48
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