Brain development (sulci and gyri) as assessed by early postnatal MR imaging in preterm and term newborn infants

Details

Serval ID
serval:BIB_880914C4BCF9
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Brain development (sulci and gyri) as assessed by early postnatal MR imaging in preterm and term newborn infants
Journal
Neuropediatrics
Author(s)
Ruoss  K., Lovblad  K., Schroth  G., Moessinger  A. C., Fusch  C.
ISSN
0174-304X (Print)
Publication state
Published
Issued date
04/2001
Volume
32
Number
2
Pages
69-74
Notes
Journal Article --- Old month value: Apr
Abstract
OBJECTIVE: To investigate fetal brain development in vivo using early postnatal cranial MRI in term and preterm newborn infants. STUDY DESIGN: 51 infants, 1.5-T whole-body system, extremity coil, spin-echo images obtained in all three planes (T1- and T2-weighted). Independent review by two neuroradiologists (blinded for gestational age and medical history) regarding the development of 12 sulci and 10 gyri using a modified scoring system. Gestational age was obtained either by ultrasound or from the first day of the last menstrual period. Exclusion criteria: head circumference <10th or >90th percentile, cerebral malformation, chromosomal/metabolic disorder. RESULTS AND CONCLUSION: Age at study ranged from 23 5/7-43 0/7 postmenstrual weeks. Brain maturation starts in the central area and proceeds towards the parieto-occipital cortex. The frontal cortex develops last. Transition to degrees 1, degrees 2 and, degrees 3 starts at week 25, 32 and 35 in the central cortex and is completed at week 34, 36 and 39, respectively. Our data compare favourably with the two previously published reports about brain maturation. Early MR imaging seems therefore to be suited to study maturation of the fetal brain. This may be of pathophysiological relevance in neonatal intensive care and neurological follow-up studies.
Keywords
Birth Weight Brain/anatomy & histology/*growth & development Cerebral Cortex/anatomy & histology/growth & development Female Gestational Age Humans Infant, Newborn Infant, Premature/*growth & development Infant, Small for Gestational Age *Magnetic Resonance Imaging Male Reference Values
Pubmed
Web of science
Create date
25/01/2008 13:16
Last modification date
20/08/2019 14:47
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