Update of the drug resistance mutations in HIV-1: Fall 2005.

Details

Serval ID
serval:BIB_87FE63214720
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Update of the drug resistance mutations in HIV-1: Fall 2005.
Journal
Topics in HIV Medicine
Author(s)
Johnson V.A., Brun-Vezinet F., Clotet B., Conway B., Kuritzkes D.R., Pillay D., Schapiro J.M., Telenti A., Richman D.D.
ISSN
1542-8826
Publication state
Published
Issued date
11/2005
Volume
13
Number
4
Pages
125-131
Language
english
Notes
Publication types: Journal Article
Abstract
The International AIDS Society-USA (IAS-USA) Drug Resistance Mutations Group is marking 5 years as an independent volunteer panel of experts focused on identifying key HIV-1 drug resistance mutations. The goal of the effort is to quickly deliver accurate and unbiased information on these mutations to HIV clinical practitioners. The October/November 2005 version of the IAS-USA Drug Resistance Mutations Figures replaces the version published in this journal in March/April 2005. The IAS-USA Drug Resistance Mutations Figures are designed for use in identifying mutations associated with viral resistance to antiretroviral drugs and in making therapeutic decisions. Care should be taken when using this list of mutations for surveillance or epidemiologic studies of transmission of drug-resistant virus. A number of amino acid substitutions, particularly minor mutations, represent polymorphisms that in isolation may not reflect prior drug selective pressure or reduced drug susceptibility.
Keywords
Anti-HIV Agents/pharmacology, Drug Resistance, Viral/genetics, HIV Infections/drug therapy, HIV Protease Inhibitors/pharmacology, HIV-1/genetics, Humans, Mutation, Reverse Transcriptase Inhibitors/pharmacology
Pubmed
Create date
25/01/2008 14:45
Last modification date
20/08/2019 14:47
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