Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes.

Details

Serval ID
serval:BIB_874A5FF2AFFC
Type
Article: article from journal or magazin.
Collection
Publications
Title
Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes.
Journal
Forensic Science International
Author(s)
Roewer L., Krawczak M., Willuweit S., Nagy M., Alves C., Amorim A., Anslinger K., Augustin C., Betz A., Bosch E., Cagliá A., Carracedo A., Corach D., Dekairelle A.F., Dobosz T., Dupuy B.M., Füredi S., Gehrig C., Gusmaõ L., Henke J., Henke L., Hidding M., Hohoff C., Hoste B., Jobling M.A., Kärgel H.J., de Knijff P., Lessig R., Liebeherr E., Lorente M., Martínez-Jarreta B., Nievas P., Nowak M., Parson W., Pascali V.L., Penacino G., Ploski R., Rolf B., Sala A., Schmidt U., Schmitt C., Schneider P.M., Szibor R., Teifel-Greding J., Kayser M.
ISSN
0379-0738
Publication state
Published
Issued date
2001
Volume
118
Number
2-3
Pages
106-113
Language
english
Abstract
The reference database of highly informative Y-chromosomal short tandem repeat (STR) haplotypes (YHRD), available online at http://ystr.charite.de, represents the largest collection of male-specific genetic profiles currently available for European populations. By September 2000, YHRD contained 4688 9-locus (so-called "minimal") haplotypes, 40% of which have been extended further to include two additional loci. Establishment of YHRD has been facilitated by the joint efforts of 31 forensic and anthropological institutions. All contributing laboratories have agreed to standardize their Y-STR haplotyping protocols and to participate in a quality assurance exercise prior to the inclusion of any data. In view of its collaborative character, and in order to put YHRD to its intended use, viz. the support of forensic caseworkers in their routine decision-making process, the database has been made publicly available via the Internet in February 2000. Online searches for complete or partial Y-STR haplotypes from evidentiary or non-probative material can be performed on a non-commercial basis, and yield observed haplotype counts as well as extrapolated population frequency estimates. In addition, the YHRD website provides information about the quality control test, genotyping protocols, haplotype formats and informativity, population genetic analysis, literature references, and a list of contact addresses of the contributing laboratories.
Keywords
Databases, Factual, Europe, Genetics, Population, Haplotypes, Humans, Male, Tandem Repeat Sequences, Y Chromosome
Pubmed
Create date
28/03/2009 11:38
Last modification date
20/08/2019 14:46
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