Pipe smoking and cancers of the upper digestive tract

Details

Serval ID
serval:BIB_872D4F60DC13
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Pipe smoking and cancers of the upper digestive tract
Journal
International Journal of Cancer
Author(s)
Randi  Giorgia, Scotti  Lorenza, Bosetti  Cristina, Talamini  Renato, Negri  Eva, Levi  Fabio, Franceschi  Silvia, La Vecchia  Carlo
ISSN
0020-7136
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
121
Number
9
Pages
2049-2051
Language
english
Abstract
Pipe smoking has been related to the risk of cancers of the upper digestive and respiratory tract, but quantification of the risk for exclusive pipe smokers is still limited. To analyse the association between exclusive pipe smoking and cancers of the upper digestive tract, we used data from a series of case-control studies conducted in Italy and Switzerland between 1984 and 1999. After excluding cigarette and cigar smokers, 41 male oral and pharyngeal cancer cases, 52 male oesophageal cancer cases and 1,032 male controls were included in the present analysis. Odds ratios (OR) of cancers were estimated by the mean of unconditional multivariate logistic regression, including terms for age, study centre, education, body mass index, and alcohol drinking. Compared to never smokers, exclusive pipe smokers had an OR of 8.7 [95% confidence intervals (CI): 4.0-18.9] of all upper digestive tract cancers. The OR was 12.6 for oral and pharyngeal and 7.2 for oesophageal cancer. Pipe smokers who were also heavy alcohol drinkers had an OR of 38.8 (95% CI: 13.6-110.9) as compared to never smokers and light drinkers. Thus, pipe smoking and heavy alcohol drinking appears to interact at least on a multiplicative model. [Ed.]
Keywords
Pharyngeal Neoplasms , Smoking
Pubmed
Web of science
Create date
05/02/2008 10:16
Last modification date
20/08/2019 14:46
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