Immunothérapie: une nouvelle arme contre le cancer de la prostate [Immunotherapy: a therapeutic revolution against prostate cancer?].

Details

Serval ID
serval:BIB_872CCC33F242
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Immunothérapie: une nouvelle arme contre le cancer de la prostate [Immunotherapy: a therapeutic revolution against prostate cancer?].
Journal
Revue Médicale Suisse
Author(s)
Pracht M., Herrera F., Tawadros T., Berthold D.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2013
Volume
9
Number
387
Pages
1070-1075
Language
french
Notes
Publication types: English Abstract ; Journal Article
Abstract
The interaction between the immune system and cancer was an area of research interest for several decades. The recent U.S. Food and Drug Administration approval of sipuleucel-T and ipilimumab stimulated broader interest in manipulating immunity to fight cancer. In the context of prostate cancer, the immunotherapy strategies under development are therapeutic vaccination strategies, such as sipuleucel-T and PROSTVAC-VF, or immune checkpoint blockade of CTLA-4. Improved understanding of the immune responses generated by the development of predictive biomarkers for patient selection will guide rational combinations of these treatments and provide new treatment options in prostate cancer.
Keywords
Humans, Immunotherapy, Male, Prostatic Neoplasms/drug therapy, Prostatic Neoplasms/immunology
Pubmed
Create date
19/09/2013 20:15
Last modification date
20/08/2019 14:46
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