Automated analysis of background EEG and reactivity during therapeutic hypothermia in comatose patients after cardiac arrest.

Details

Serval ID
serval:BIB_866BA32B7A2D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Automated analysis of background EEG and reactivity during therapeutic hypothermia in comatose patients after cardiac arrest.
Journal
Clinical EEG and Neuroscience
Author(s)
Noirhomme Q., Lehembre R., Lugo Zdel R, Lesenfants D., Luxen A., Laureys S., Oddo M., Rossetti A.O.
ISSN
1550-0594 (Print)
ISSN-L
1550-0594
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
45
Number
1
Pages
6-13
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Visual analysis of electroencephalography (EEG) background and reactivity during therapeutic hypothermia provides important outcome information, but is time-consuming and not always consistent between reviewers. Automated EEG analysis may help quantify the brain damage. Forty-six comatose patients in therapeutic hypothermia, after cardiac arrest, were included in the study. EEG background was quantified with burst-suppression ratio (BSR) and approximate entropy, both used to monitor anesthesia. Reactivity was detected through change in the power spectrum of signal before and after stimulation. Automatic results obtained almost perfect agreement (discontinuity) to substantial agreement (background reactivity) with a visual score from EEG-certified neurologists. Burst-suppression ratio was more suited to distinguish continuous EEG background from burst-suppression than approximate entropy in this specific population. Automatic EEG background and reactivity measures were significantly related to good and poor outcome. We conclude that quantitative EEG measurements can provide promising information regarding current state of the patient and clinical outcome, but further work is needed before routine application in a clinical setting.
Pubmed
Web of science
Create date
17/02/2014 7:37
Last modification date
20/08/2019 14:45
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