Factors associated with comorbidity patterns in full and partial PTSD: Findings from the PsyCoLaus study.

Details

Ressource 1Download: BIB_86376A33BB71.P001.pdf (268.50 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_86376A33BB71
Type
Article: article from journal or magazin.
Collection
Publications
Title
Factors associated with comorbidity patterns in full and partial PTSD: Findings from the PsyCoLaus study.
Journal
Comprehensive Psychiatry
Author(s)
Müller M., Vandeleur C., Rodgers S., Rössler W., Castelao E., Preisig M., Ajdacic-Gross V.
ISSN
1532-8384 (Electronic)
ISSN-L
0010-440X
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
55
Number
4
Pages
837-848
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Subtypes of comorbid conditions and their associated trauma and clinical characteristics in full and partial PTSD were examined. Data from 289 subjects from the general population that met criteria for full or partial PTSD were analyzed. Latent class analyses (LCA) were performed to derive homogeneous patterns of DSM-IV Axis-I disorders and anti-social personality comorbid to PTSD. Logistic regression models were conducted to characterize these classes by trauma-related and clinical features. The LCA revealed three classes: (1) low comorbidity; (2) high comorbidity with primarily substance-related disorders and a higher proportion of males; and (3) more severe PTSD-symptomatology and higher comorbid anxiety disorders and depression, almost entirely represented by females. Exposure to sexual abuse was more likely in the substance-dependent class and contributed strongly to the distinction between classes. Affective disorders tended to precede the onset of PTSD in the substance-dependent class, whereas phobias were more likely to follow PTSD in the depressed-anxious class. Posttrauma onset of alcohol use disorders in the substance dependent class confirmed the self-medication hypothesis. The three classes of comorbidity and their sequence of onset with PTSD suggest different mechanisms involved in their development. Our findings suggest that PTSD-related comorbidity subtypes also apply to individuals with partial PTSD.
Pubmed
Web of science
Open Access
Yes
Create date
25/04/2014 13:18
Last modification date
20/08/2019 15:45
Usage data