Screening for foetal malformations: performance of routine ultrasonography in the population of the Swiss Canton of Vaud.
Details
State: Public
Version: Final published version
Serval ID
serval:BIB_8632C6F5B661
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Screening for foetal malformations: performance of routine ultrasonography in the population of the Swiss Canton of Vaud.
Journal
Swiss Medical Weekly
ISSN
1424-7860
Publication state
Published
Issued date
2001
Peer-reviewed
Oui
Volume
131
Number
33-34
Pages
490-494
Language
english
Abstract
OBJECTIVE: To determine the sensitivity of ultrasonography in screening for foetal malformations in the pregnant women of the Swiss Canton of Vaud. STUDY DESIGN: Retrospective study over a period of five years. METHOD: We focused our study on 512 major or minor clinically relevant malformations detectable by ultrasonography. We analysed the global sensitivity of the screening and compared the performance of the tertiary centre with that of practitioners working in private practice or regional hospitals. RESULTS: Among the 512 malformations, 181 (35%) involved the renal and urinary tract system, 137 (27%) the heart, 71 (14%) the central nervous system, 50 (10%) the digestive system, 42 (8%) the face and 31 (6%) the limbs. Global sensitivity was 54.5%. The lowest detection rate was observed for cardiac anomalies, with only 23% correct diagnoses. The tertiary centre achieved a 75% detection rate in its outpatient clinic and 83% in referred patients. Outside the referral centre, the diagnostic rate attained 47%. CONCLUSIONS: Routine foetal examination by ultrasonography in a low-risk population can detect foetal structural abnormalities. Apart from the diagnosis of cardiac abnormalities, the results in the Canton of Vaud are satisfactory and justify routine screening for malformations in a low-risk population. A prerequisite is continuing improvement in the skills of ultrasonographers through medical education.
Keywords
Central Nervous System, Congenital Abnormalities, Digestive System, Digestive System Abnormalities, Female, Fetus, Heart Defects, Congenital, Humans, Mass Screening, Musculoskeletal Abnormalities, Pregnancy, Prevalence, Retrospective Studies, Sensitivity and Specificity, Switzerland, Ultrasonography, Prenatal
Pubmed
Web of science
Create date
28/02/2008 12:52
Last modification date
20/08/2019 15:45