Radioguided occult colonic lesion identification (ROCLI) during open and laparoscopic surgery

Details

Serval ID
serval:BIB_8614F4074ACA
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Radioguided occult colonic lesion identification (ROCLI) during open and laparoscopic surgery
Journal
Tumori
Author(s)
Rezzo  R., Scopinaro  G., Gambaro  M., Michetti  P., Anfossi  G.
ISSN
0300-8916 (Print)
Publication state
Published
Issued date
06/2002
Volume
88
Number
3
Pages
S19-22
Notes
Journal Article --- Old month value: May-Jun
Abstract
AIMS AND BACKGROUND: Intraoperative localization, during open and laparoscopic surgery, of small, nonpalpable colonic lesions located at peculiar sites or with concurrent inflammatory bowel alterations (diverticulosis, perivisceritis) is often difficult. The aim of our work was to assess the validity of radioguided identification after preoperative labeling. METHODS AND STUDY DESIGN: Patients who were candidates for colon surgery for occult lesions that, because of their size and location, were assumed to be difficult to detect, underwent colonoscopy 1 to 2.5 hours before surgery. A small dose of labeled albumin macroaggregates was injected with a sclerotherapy needle into the subserosa underneath the lesion. Immediately following the injection the lesion was identified with a transcutaneously placed gamma detecting probe. Intraoperative tracer detection was performed either during open surgery or by means of a laparoscopic probe (detection time 3-5 mins). The position of the lesion was marked with a suture or with a clip. Surgery was performed according to the type of lesion to be treated. RESULTS: In our initial clinical experience 15 colon lesions were preoperatively marked in 14 patients and were subsequently detected during surgery (four under laparoscopy) with a gamma detecting probe. This technique allows highly accurate, fast, and inexpensive surgical localization of lesions without irradiation and without complications. CONCLUSION: Our experience shows that preoperative endoscopic marking of nonpalpable colon lesions with 99mTc-labeled albumin macroaggregates followed by intraoperative detection with a gamma probe is a useful clinical method that is highly accurate and without complications.
Keywords
Colonic Neoplasms/*radionuclide imaging/*surgery Diagnosis, Differential Humans Laparoscopy Laparotomy Neoplasms, Unknown Primary/*radionuclide imaging/*surgery
Pubmed
Web of science
Create date
25/01/2008 16:01
Last modification date
20/08/2019 14:45
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