Anatomic constraints on cognitive theories of category specificity.

Details

Serval ID
serval:BIB_8608396BAA6F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Anatomic constraints on cognitive theories of category specificity.
Journal
Neuroimage
Author(s)
Devlin J.T., Moore C.J., Mummery C.J., Gorno-Tempini M.L., Phillips J.A., Noppeney U., Frackowiak R.S., Friston K.J., Price C.J.
ISSN
1053-8119 (Print)
ISSN-L
1053-8119
Publication state
Published
Issued date
2002
Volume
15
Number
3
Pages
675-685
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
Many cognitive theories of semantic organization stem from reports of patients with selective, category-specific deficits for particular classes of objects (e.g., fruit). The anatomical assumptions underlying the competing claims can be evaluated with functional neuroimaging but the findings to date have been inconsistent and insignificant when standard statistical criteria are adopted. We hypothesized that category differences in functional brain responses might be small and task dependent. To test this hypothesis, we entered data from seven PET studies into a single multifactorial design which crossed category (living vs man-made) with a range of tasks. Reliable category-specific effects were observed but only for word retrieval and semantic decision tasks. Living things activated medial aspects of the anterior temporal poles bilaterally while tools activated a left posterior middle temporal region. These category-by-task interactions provide robust evidence for an anatomical double dissociation according to category and place strong constraints on cognitive theories of the semantic system. Furthermore they reconcile some of the apparent inconsistencies between lesion studies and functional neuroimaging data.
Keywords
Adult, Attention/physiology, Brain Mapping, Cerebral Cortex/physiology, Cerebral Cortex/radionuclide imaging, Discrimination Learning/physiology, Female, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Male, Mental Recall/physiology, Middle Aged, Paired-Associate Learning/physiology, Pattern Recognition, Visual/physiology, Problem Solving/physiology, Semantics, Tomography, Emission-Computed
Pubmed
Web of science
Create date
12/09/2011 17:37
Last modification date
20/08/2019 14:45
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