Maladies respiratoires et oxydants. [Respiratory diseases and oxidants]

Details

Serval ID
serval:BIB_8558E06AB397
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Maladies respiratoires et oxydants. [Respiratory diseases and oxidants]
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Leuenberger  P.
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
01/1994
Volume
124
Number
4
Pages
129-35
Notes
English Abstract
Journal Article
Review --- Old month value: Jan 29
Abstract
Oxidants play a major role in mediating a variety of human disorders. The sources of oxidants may vary. They can be released by activated inflammatory cells or derive from the environment (such as pollution or tobacco smoke). In addition to acute, usually reversible reactions, numerous pulmonary diseases are associated with long lasting oxidant stress (adult respiratory distress syndrome, drug induced lung lesions, chronic obstructive pulmonary diseases, asthma, emphysema, interstitial fibrosis). Therapeutic action aimed at increasing anti-oxidant defense mechanisms is still a clinical challenge. Administration of N-acetylcysteine by the oral route is a simple and efficacious means of correcting oxidant-antioxidant imbalance.
Keywords
Antioxidants/therapeutic use Humans Lung Diseases/chemically induced Lung Diseases, Obstructive/chemically induced Oxidants/*adverse effects Oxidants, Photochemical/*adverse effects Peroxides/metabolism Respiratory Tract Diseases/*chemically induced/drug therapy Superoxides/metabolism Tobacco Smoke Pollution
Pubmed
Web of science
Create date
25/01/2008 9:50
Last modification date
20/08/2019 14:44
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