Synchronous and baroceptor-sensitive oscillations in skin microcirculation: evidence for central autonomic control.

Details

Serval ID
serval:BIB_8537C1B81336
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Synchronous and baroceptor-sensitive oscillations in skin microcirculation: evidence for central autonomic control.
Journal
The American journal of physiology
Author(s)
Bernardi L., Hayoz D., Wenzel R., Passino C., Calciati A., Weber R., Noll G.
ISSN
0363-6135
0002-9513
Publication state
Published
Issued date
1997
Volume
273
Number
4 Pt 2
Pages
H1867-78
Language
english
Notes
Publication types: Journal Article - Publication Status: ppublish
Abstract
To determine whether skin blood flow is local or takes part in general regulatory mechanisms, we recorded laser-Doppler flowmetry (LDF; left and right index fingers), blood pressure, muscle sympathetic nerve activity (MSNA), R-R interval, and respiration in 10 healthy volunteers and 3 subjects after sympathectomy. We evaluated 1) the synchronism of LDF fluctuations in two index fingers, 2) the relationship with autonomically mediated fluctuations in other signals, and 3) the LDF ability to respond to arterial baroreflex stimulation (by neck suction at frequencies from 0.02 to 0.20 Hz), using spectral analysis (autoregressive uni- and bivariate, time-variant algorithms). Synchronous LDF fluctuations were observed in the index fingers of healthy subjects but not in sympathectomized patients. LDF fluctuations were coherent with those obtained for blood pressure, MSNA, and R-R interval. LDF fluctuations were leading blood pressure in the low-frequency (LF; 0.1 Hz) band and lagging in the respiratory, high-frequency (HF; approximately 0.25 Hz) band, suggesting passive "downstream" transmission only for HF and "upstream" transmission for LF from the microvessels. LDF fluctuations were responsive to sinusoidal neck suction up to 0.1 Hz, indicating response to sympathetic modulation. Skin blood flow thus reflects modifications determined by autonomic activity, detectable by frequency analysis of spontaneous fluctuations.
Keywords
Adult, Arteries, Autonomic Nervous System, Baroreflex, Blood Pressure, Brain, Fingers, Heart Rate, Humans, Hyperhidrosis, Laser-Doppler Flowmetry, Microcirculation, Muscles, Oscillometry, Pressoreceptors, Reference Values, Skin, Sympathectomy, Sympathetic Nervous System, Time Factors
Pubmed
Create date
17/01/2008 16:38
Last modification date
20/08/2019 14:44
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