Sonographic detection of central nervous system defects in the first trimester of pregnancy.

Details

Serval ID
serval:BIB_8324CF4AE305
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Sonographic detection of central nervous system defects in the first trimester of pregnancy.
Journal
Prenatal diagnosis
Author(s)
Engels A.C., Joyeux L., Brantner C., De Keersmaecker B., De Catte L., Baud D., Deprest J., Van Mieghem T.
ISSN
1097-0223 (Electronic)
ISSN-L
0197-3851
Publication state
Published
Issued date
03/2016
Peer-reviewed
Oui
Volume
36
Number
3
Pages
266-273
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
The fetal central nervous system can already be examined in the first trimester of pregnancy. Acrania, alobar holoprosencephaly, cephaloceles, and spina bifida can confidently be diagnosed at that stage and should actively be looked for in every fetus undergoing first-trimester ultrasound. For some other conditions, such as vermian anomalies and agenesis of the corpus callosum, markers have been identified, but the diagnosis can only be confirmed in the second trimester of gestation. For these conditions, data on sensitivity and more importantly specificity and false positives are lacking, and one should therefore be aware not to falsely reassure or scare expecting parents based on first-trimester findings. This review summarizes the current knowledge of first-trimester neurosonography in the normal and abnormal fetus and gives an overview of which diseases can be diagnosed.

Keywords
Central Nervous System Diseases/congenital, Central Nervous System Diseases/diagnostic imaging, Echoencephalography, Female, Fetal Diseases/diagnostic imaging, Fetus/abnormalities, Fetus/diagnostic imaging, Humans, Nervous System Malformations/diagnostic imaging, Pregnancy, Pregnancy Trimester, First, Ultrasonography, Prenatal
Pubmed
Create date
26/04/2016 16:49
Last modification date
20/08/2019 14:43
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