Lymphoproliferative disorders associated with hypereosinophilia.

Details

Serval ID
serval:BIB_82D163A9066D
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Lymphoproliferative disorders associated with hypereosinophilia.
Journal
Seminars In Hematology
Author(s)
Roufosse F., Garaud S., de Leval L.
ISSN
1532-8686 (Electronic)
ISSN-L
0037-1963
Publication state
Published
Issued date
2012
Volume
49
Number
2
Pages
138-148
Language
english
Abstract
Hypereosinophilia, defined as peripheral blood eosinophil counts >1,500/μL, may complicate the course of various lymphoproliferative disorders. Among these, Hodgkin lymphoma (HL) and certain peripheral T-cell lymphomas (PTCLs) derived from CD4 cells, including Sezary syndrome (SS), adult T-cell leukemia/lymphoma (ATLL), and angioimmunoblastic T-cell lymphoma (AITL), are most commonly associated with increased reactive eosinophilopoiesis. Rarely, marked hypereosinophilia (HE) may occur in the setting of acute B-cell lymphoblastic leukemia, with a substantial impact on disease course. The mechanisms leading to blood and tissue eosinophilia in the setting of lymphoproliferative disorders, as well as the clinical complications and prognostic implications of hypereosinophilia, are discussed in this review.
Pubmed
Web of science
Create date
30/03/2012 10:00
Last modification date
20/08/2019 14:42
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