Plaque progression: Where, why, and how fast? A review of what we have learned from the analysis of patient data from the PARADIGM registry.

Details

Serval ID
serval:BIB_82A95D608C65
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Plaque progression: Where, why, and how fast? A review of what we have learned from the analysis of patient data from the PARADIGM registry.
Journal
Journal of cardiovascular computed tomography
Author(s)
Indraratna P., Khasanova E., Gulsin G.S., Tzimas G., Takagi H., Park K.H., Lin F.Y., Shaw L.J., Lee S.E., Narula J., Bax J.J., Chang H.J., Leipsic J.
Working group(s)
PARADIGM investigators
ISSN
1876-861X (Electronic)
ISSN-L
1876-861X
Publication state
Published
Issued date
2022
Peer-reviewed
Oui
Volume
16
Number
4
Pages
294-302
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Ischemic heart disease is the most common cause of mortality worldwide. The pathophysiology of myocardial infarction relates to temporal changes of atherosclerotic plaque culminating in plaque rupture, erosion or hemorrhage and the subsequent thrombotic response. Coronary computed tomographic angiography (CCTA) provides the ability to visualize and quantify plaque, and plaque progression can be measured on a per-patient basis by comparing findings of serial CCTA. The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry was established with the objective of identifying patterns of plaque progression in a large population. The registry comprises over 2000 patients with multiple CCTA scans performed at least two years apart. Unlike previous CCTA registries, a semi-automated plaque quantification technique permitting detailed analysis of plaque progression was performed on all patients with interpretable studies. Since the registry was established, 19 peer-reviewed publications were identified, and all are reviewed and summarized in this article.
Keywords
Computed Tomography Angiography/methods, Coronary Angiography/methods, Coronary Artery Disease/diagnostic imaging, Disease Progression, Humans, Plaque, Atherosclerotic, Predictive Value of Tests, Prospective Studies, Registries, Atherosclerosis, Coronary computed tomography angiography coronary artery disease, Myocardial infarction
Pubmed
Web of science
Create date
03/12/2021 12:09
Last modification date
21/11/2023 8:09
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