Cryoablation of Extra-Abdominal Desmoid Tumors: A Single-Center Experience with Literature Review.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_8281ACBA56C2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cryoablation of Extra-Abdominal Desmoid Tumors: A Single-Center Experience with Literature Review.
Journal
Diagnostics
Author(s)
Saltiel S., Bize P.E., Goetti P., Gallusser N., Cherix S., Denys A., Becce F., Tsoumakidou G.
ISSN
2075-4418 (Print)
ISSN-L
2075-4418
Publication state
Published
Issued date
04/08/2020
Peer-reviewed
Oui
Volume
10
Number
8
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Cryoablation (CA) has gained popularity in the treatment of benign and malignant musculoskeletal tumors. While extra-abdominal desmoid (EAD) tumors are not malignant, they remain challenging to treat because of their high local recurrence rate. We reviewed all EAD tumors treated with CA at our institution between November 2012 and March 2020. Fourteen procedures were performed on nine females and one male (mean age, 33 ± 18 years) as either first-line (n = 4) or salvage therapy (n = 6) with curative intent (n = 8) or tumor debulking (n = 2). Mean tumor size was 63.6 cm <sup>3</sup> (range, 3.4-169 cm <sup>3</sup> ). Contrast-enhanced MRI was performed before treatment and at 3-, 6-, and 12-month follow-up. Treatment outcome was based on the change in enhanced tumor volume (ET-V). For curatively treated patients, the mean ET-V change was -97 ± 7%, -44 ± 143%, and +103 ± 312% at 3, 6, and 12 months, respectively. For debulking patients, the mean ET-V change was -98 ± 4%, +149 ± 364%, and +192 ± 353% at 3, 6, and 12 months, respectively. During a mean follow-up of 53.7 months (range, 12-83 months), one grade III and one grade IV complication were noted. We found CA to be safe and well tolerated in patients with EAD.
Keywords
aggressive fibromatosis, cryoablation, cryotherapy, extra-abdominal desmoid tumor, magnetic resonance imaging, treatment outcome
Pubmed
Web of science
Open Access
Yes
Create date
17/08/2020 11:15
Last modification date
15/01/2021 8:10
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