Willed action and the prefrontal cortex in man: a study with PET.

Details

Serval ID
serval:BIB_82583039B6BE
Type
Article: article from journal or magazin.
Collection
Publications
Title
Willed action and the prefrontal cortex in man: a study with PET.
Journal
Proceedings of the Royal Society B Biological Sciences
Author(s)
Frith C.D., Friston K., Liddle P.F., Frackowiak R.S.
ISSN
0962-8452 (Print)
ISSN-L
0962-8452
Publication state
Published
Issued date
1991
Volume
244
Number
1311
Pages
241-246
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
We used positron emission tomography to contrast changes in cerebral blood flow associated with willed and routine acts. In the six tasks used, volunteers had to make a series of responses to a sequence of stimuli. For the routine acts, each response was completely specified by the stimulus. For the willed acts, the response was open-ended and therefore volunteers had to make a deliberate choice. Willed acts in the two response modalities studied (speaking a word, or lifting a finger) were associated with increased blood flow in the dorsolateral prefrontal cortex (Brodmann area 46). Willed acts were also associated with decreases in blood flow, but the location of these decreases was modality dependent.
Keywords
Acoustic Stimulation, Adult, Cerebral Cortex/blood supply, Cerebral Cortex/physiology, Choice Behavior, Fingers/innervation, Humans, Male, Mental Processes, Organ Specificity, Speech, Tomography, Emission-Computed/methods, Touch
Pubmed
Web of science
Create date
06/10/2011 17:18
Last modification date
20/08/2019 14:42
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