Usefulness of cardiovascular magnetic resonance imaging to predict the need for intervention in patients with coarctation of the aorta.

Details

Serval ID
serval:BIB_81C3820EE91F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Usefulness of cardiovascular magnetic resonance imaging to predict the need for intervention in patients with coarctation of the aorta.
Journal
The American journal of cardiology
Author(s)
Muzzarelli S., Meadows A.K., Ordovas K.G., Higgins C.B., Meadows J.J.
ISSN
1879-1913 (Electronic)
ISSN-L
0002-9149
Publication state
Published
Issued date
15/03/2012
Peer-reviewed
Oui
Volume
109
Number
6
Pages
861-865
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Cardiovascular magnetic resonance (CMR) imaging can predict hemodynamically significant coarctation of the aorta (CoA) with a high degree of discrimination. However, the ability of CMR to predict important clinical outcomes in this patient population is unknown. Therefore, we sought to define the ability of CMR to predict the need for surgical or transcatheter intervention in patients with CoA. We retrospectively reviewed the data from 133 consecutive patients who had undergone CMR for the evaluation of known or suspected CoA. The characteristics of the CMR-derived variables predicting the need for surgical or transcatheter intervention for CoA within 1 year were determined through logistic regression analysis. Therapeutic aortic intervention was performed in 41 (31%) of the 133 patients during the study period. The indexed minimum aortic cross-sectional area was the strongest predictor of subsequent intervention (area under the receiver operating characteristic curve 0.975) followed by heart rate-corrected deceleration time in the descending aorta (area under the receiver operating characteristic curve 0.951), and the percentage of flow increase (area under the receiver operating characteristic curve 0.867). The combination of the indexed minimum aortic cross-sectional area and rate-corrected deceleration time in the descending aorta provided the best predictive model (area under the receiver operating characteristic curve 0.986). In conclusion, CMR findings can predict the need for subsequent intervention in CoA. These findings reinforce the "gate-keeper role" of CMR to cardiac catheterization by providing valuable diagnostic and powerful prognostic information and could guide additional treatment of patients with CoA with the final intent of reducing the number of diagnostic catheterizations in such patients.
Keywords
Adolescent, Adult, Aortic Coarctation/diagnosis, Aortic Coarctation/physiopathology, Aortic Coarctation/surgery, Blood Flow Velocity, Child, Child, Preschool, Diagnosis, Differential, Female, Follow-Up Studies, Humans, Infant, Magnetic Resonance Imaging, Cine/statistics & numerical data, Male, Middle Aged, Predictive Value of Tests, Retrospective Studies, Sensitivity and Specificity, Severity of Illness Index, Young Adult
Pubmed
Web of science
Create date
15/11/2017 17:10
Last modification date
23/02/2024 15:04
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