Changes in mental and sexual health among MSM using HIV pre-exposure prophylaxis during the SARS-CoV-2 pandemic: longitudinal analysis of the SwissPrEPared cohort study.

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Ressource 1Download: 2022 WINTER et al. Changes in mental and sexual health among MSM using PrEP during COVID SMW.pdf (2506.07 [Ko])
State: Public
Version: Final published version
License: CC BY-NC-SA 4.0
Serval ID
serval:BIB_80B3E54B7ADE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Changes in mental and sexual health among MSM using HIV pre-exposure prophylaxis during the SARS-CoV-2 pandemic: longitudinal analysis of the SwissPrEPared cohort study.
Journal
Swiss medical weekly
Author(s)
Winter B.L., Hovaguimian F., Kouyos R.D., Schmidt A.J., Bernasconi E., Braun D.L., Calmy A., Notter J., Stoeckle M., Surial B., Christinet V., Cavassini M., Depmeier C., Läuchli S., Boffi El Amari E., Reinacher M., Rasi M., Bruggmann P., Haerry D., Bize R., Low N., Lehner A., Quednow B.B., Fehr J.S., Hampel B.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Publication state
Published
Issued date
20/06/2022
Peer-reviewed
Oui
Volume
152
Pages
w30192
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Changes in mental and sexual health among men having sex with men (MSM) due to the SARS-CoV-2 pandemic remain unclear.
Design: Longitudinal analysis of an ongoing, multicentre, pre-exposure prophylaxis (PrEP) cohort (NCT03893188) in Switzerland. Participants: HIV-negative MSM aged ≥18 who completed at least one questionnaire before and one after the start of the SARS-CoV-2 pandemic. Outcomes: Primary: mental health, defined as anxiety and depression scores assessed by the Patient Health Questionnaire-4. Secondary: sexual behaviour, well-being, PrEP use and disruption of care. Outcomes were assessed over seven periods corresponding to different SARS-CoV-2 prevention measures in Switzerland. We performed pairwise comparisons between periods (Wilcoxon signed rank test).
Data from 1,043 participants were included. Whilst anxiety scores remained stable over time, depression scores worsened in the second wave and the second lockdown period compared to pre-pandemic scores. This was confirmed by pairwise comparisons (pre-SARS-CoV-2/second wave and pre-SARS-CoV-2/second lockdown: p <0.001). Downward trends in sexual activity,sexualized substance use, and a switch from daily to "event-driven" PrEP were found. Disruption of care affected 42.6% (790/1856) of daily PrEP users' follow-up visits.
In this longitudinal analysis of a PrEP cohort enrolling MSM, depression scores worsened in the second wave and the second lockdown compared to the pre-pandemic period.
Keywords
COVID-19/prevention & control, Cohort Studies, Communicable Disease Control, HIV Infections/drug therapy, HIV Infections/epidemiology, HIV Infections/prevention & control, Homosexuality, Male, Humans, Male, Pandemics/prevention & control, Pre-Exposure Prophylaxis, SARS-CoV-2, Sexual Behavior, Sexual Health, Sexual and Gender Minorities
Pubmed
Open Access
Yes
Create date
04/07/2022 12:40
Last modification date
08/07/2022 7:10
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