Hepatitis C. [Hepatitis C]

Details

Serval ID
serval:BIB_7F3AEC667945
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hepatitis C. [Hepatitis C]
Journal
Therapeutische Umschau
Author(s)
Moradpour  D., Blum  H. E.
ISSN
0040-5930 (Print)
Publication state
Published
Issued date
08/2004
Volume
61
Number
8
Pages
493-8
Notes
Comparative Study
English Abstract
Journal Article
Review --- Old month value: Aug
Abstract
Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Here, we briefly review the virology, diagnosis and therapy of hepatitis C. Standard therapy with pegylated interferon-alpha and ribavirin results in a sustained virological response in 40-50% of genotype 1- and in about 80% of genotype 2- or 3-infected patients. Recent progress has allowed the identification of novel antiviral targets and therapeutic strategies. These will likely complement existing therapeutic modalities in the near future.
Keywords
Acute Disease Antiviral Agents/administration & dosage/therapeutic use Carcinoma, Hepatocellular/etiology Drug Therapy, Combination Genotype Hepacivirus/genetics *Hepatitis C/complications/diagnosis/drug therapy/epidemiology/virology Hepatitis C, Chronic/complications/diagnosis/drug therapy/epidemiology/virology Humans Interferon-alpha/administration & dosage/therapeutic use Liver Cirrhosis/etiology Liver Neoplasms/etiology Liver Transplantation RNA, Viral/analysis Reverse Transcriptase Polymerase Chain Reaction Ribavirin/administration & dosage/therapeutic use Time Factors
Pubmed
Create date
25/01/2008 16:05
Last modification date
20/08/2019 14:40
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