Adipocytokines in obese Ghanaian subjects with or without type 2 diabetes.

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Ressource 1Download: Adams.pdf (555.33 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_7D23B6B7516B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Adipocytokines in obese Ghanaian subjects with or without type 2 diabetes.
Journal
BMC research notes
Author(s)
Adams Y., Ofori E.K., Asare-Anane H., Amanquah S.D., Ababio G.K., Abendau E., Nabia R.
ISSN
1756-0500 (Electronic)
ISSN-L
1756-0500
Publication state
Published
Issued date
08/02/2018
Peer-reviewed
Oui
Volume
11
Number
1
Pages
109
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
This study aimed to evaluate serum leptin and high sensitivity C-reactive protein (hsCRP) concentrations in obese Ghanaians with or without type 2 diabetes and to find out the extent to which their levels are influenced by underlying disorders.
Obese subjects with type 2 diabetes had lower leptin but higher hsCRP levels compared with obese non-diabetic controls. There were negative correlations within the control group for glucose vs % muscle mass (r = - 0.378, p = 0.016), leptin vs % muscle mass (r = - 0.555, p = 0.001) and within the obese diabetic group for leptin vs % muscle mass (r = - 0.602, p = 0.001). Obese persons without diabetes were about three times more likely to have higher leptin levels compared with their obese diabetic counterparts (Odds ratio = 3.315, p < 0.001). Obese females independently had a tenfold increase in leptin levels compared with obese males.

Keywords
C-reactive protein, Leptin, Obesity, Type 2 diabetes
Pubmed
Open Access
Yes
Create date
15/02/2018 21:01
Last modification date
21/08/2019 6:09
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