Traitements des facteurs de risque cardiovasculaire et dépistage de la maladie coronarienne dans le diabète de type 2 [Treatments for cardiovascular risk factors and screening for coronary artery disease in type 2 diabetes mellitus]
Details
State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_7C9EB72E65CB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Traitements des facteurs de risque cardiovasculaire et dépistage de la maladie coronarienne dans le diabète de type 2 [Treatments for cardiovascular risk factors and screening for coronary artery disease in type 2 diabetes mellitus]
Journal
Revue medicale suisse
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
09/06/2010
Peer-reviewed
Oui
Volume
6
Number
252
Pages
1176-1181
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The recent ACCORD and DIAD studies revealed results which could modify treatments and the screening of diabetes vascular complications. Indeed, ACCORD shows no benefit on the prevention of diabetes vascular complications by aggressive treatment of hypertension or the combined treatment of the dyslipidemia. The intensive treatment of the blood glucose, if associated with severe hypoglycemias, increases mortality. DIAD revealed 20% of silent myocardial ischaemia in diabetic patients but no beneficial effect on the cardiovascular mortality. A careful reading of these studies in the light of long term studies such as UKPDS and STENO reveals that these negative results are generated by a too short follow-up and too aggressive objectives. The long term studies reveal that more realistic objectives remain beneficial.
Keywords
Coronary Disease/diagnosis, Coronary Disease/epidemiology, Coronary Disease/etiology, Coronary Disease/prevention & control, Diabetes Mellitus, Type 2/complications, Dyslipidemias/complications, Dyslipidemias/drug therapy, Evidence-Based Medicine, Fenofibrate/therapeutic use, Humans, Hypertension/complications, Hypertension/drug therapy, Hypolipidemic Agents/therapeutic use, Mass Screening, Randomized Controlled Trials as Topic, Risk Factors
Pubmed
Create date
01/10/2010 20:20
Last modification date
08/04/2025 7:14