Calcifications vasculaires et déficit en vitamine K: un facteur de risque modifiable dans l'insuffisance rénale chronique [Vascular calcifications and vitamin K deficiency: a modifiable risk factor in chronic kidney disease].
Details
Serval ID
serval:BIB_7C0C1CCD579B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Calcifications vasculaires et déficit en vitamine K: un facteur de risque modifiable dans l'insuffisance rénale chronique [Vascular calcifications and vitamin K deficiency: a modifiable risk factor in chronic kidney disease].
Journal
Revue Médicale Suisse
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2013
Volume
9
Number
375
Pages
451-455
Language
french
Notes
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Abstract
The mechanisms of vascular calcifications in chronic renal failure are complex. Apart for clotting factors, vitamin K-dependent proteins include matrix Gla protein. Glutamic acid residues in matrix Gla protein are carboxylated by vitamin K-dependent gamma-carboxylase, which enables it to inhibit calcification. The purpose of this review is to discuss available evidence implicating vitamin K as a modifiable risk factor in the pathogenesis of vascular calcification in renal diseases.
Keywords
Effect Modifier, Epidemiologic, Humans, Models, Biological, Nutritional Physiological Phenomena, Renal Insufficiency, Chronic/complications, Renal Insufficiency, Chronic/epidemiology, Risk Factors, Vascular Calcification/epidemiology, Vascular Calcification/etiology, Vitamin K/physiology, Vitamin K Deficiency/complications, Vitamin K Deficiency/epidemiology
Pubmed
Create date
07/07/2013 11:47
Last modification date
20/08/2019 15:37
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