Hypoxic peripheral chemoreflex stimulation-dependent cardiorespiratory coupling is decreased in swimmer athletes.
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State: Public
Version: author
License: CC BY 4.0
Serval ID
serval:BIB_7BC52BFBC0BC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Hypoxic peripheral chemoreflex stimulation-dependent cardiorespiratory coupling is decreased in swimmer athletes.
Journal
Physiological reports
ISSN
2051-817X (Electronic)
ISSN-L
2051-817X
Publication state
Published
Issued date
01/2024
Peer-reviewed
Oui
Volume
12
Number
1
Pages
e15890
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
Swimmer athletes showed a decreased ventilatory response and reduced sympathetic activation during peripheral hypoxic chemoreflex stimulation. Based on these observations, we hypothesized that swimmers develop a diminished cardiorespiratory coupling due to their decreased hypoxic peripheral response. To resolve this hypothesis, we conducted a study using coherence time-varying analysis to assess the cardiorespiratory coupling in swimmer athletes. We recruited 12 trained swimmers and 12 control subjects for our research. We employed wavelet time-varying spectral coherence analysis to examine the relationship between the respiratory frequency (R <sub>f</sub> ) and the heart rate (HR) time series during normoxia and acute chemoreflex activation induced by five consecutive inhalations of 100% N <sub>2</sub> . Comparing swimmers to control subjects, we observed a significant reduction in the hypoxic ventilatory responses to N <sub>2</sub> in swimmers (0.012 ± 0.001 vs. 0.015 ± 0.001 ΔV <sub>E</sub> /ΔVO <sub>2</sub> , and 0.365 ± 0.266 vs. 1.430 ± 0.961 ΔV <sub>E</sub> /ΔVCO <sub>2</sub> /ΔSpO <sub>2</sub> , both p < 0.001, swimmers vs. control, respectively). Furthermore, the coherence at the LF cutoff during hypoxia was significantly lower in swimmers compared to control subjects (20.118 ± 3.502 vs. 24.935 ± 3.832 area under curve [AUC], p < 0.012, respectively). Our findings strongly indicate that due to their diminished chemoreflex control, swimmers exhibited a substantial decrease in cardiorespiratory coupling during hypoxic stimulation.
Keywords
Humans, Athletes, Heart Rate, Hypoxia, Respiratory Rate, Time Factors, chemoreflex, coherence, hypoxia, swimmers
Pubmed
Web of science
Open Access
Yes
Create date
16/01/2024 17:41
Last modification date
23/01/2024 8:18