Combined surgery and postoperative radiation therapy for advanced laryngeal and hypopharyngeal carcinomas

Details

Serval ID
serval:BIB_7A6B742365E6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Combined surgery and postoperative radiation therapy for advanced laryngeal and hypopharyngeal carcinomas
Journal
International Journal of Radiation Oncology, Biology, Physics
Author(s)
Mirimanoff  R. O., Wang  C. C., Doppke  K. P.
ISSN
0360-3016 (Print)
Publication state
Published
Issued date
03/1985
Volume
11
Number
3
Pages
499-504
Notes
Journal Article --- Old month value: Mar
Abstract
The survival, pattern of failure and complications in 47 patients with Stage III and IV cancers of the glottis, supraglottis and hypopharynx treated with surgery and postoperative radiotherapy using a new treatment technique referred to as "mini-mantle" were analyzed. The absolute survival probability of the entire group was 53 and 31% at 3 and 5 years. The local control probability at 3 and 5 years was 63 and 58%, and was higher for the supraglottic/hypopharyngeal than for glottic carcinomas. Advanced lesions, lymph node metastases and positive resection margins were significantly related to a worse local control. Five patients developed complications requiring surgical correction, but none experienced mortality. Moderate complications were treated conservatively without lasting sequelae. This technique is a reasonably safe and efficient procedure and can be effectively employed for the management of advanced laryngeal and hypopharyngeal carcinomas after definitive surgery.
Keywords
Aged Carcinoma, Squamous Cell/radiotherapy/*surgery Combined Modality Therapy Female Humans Hypopharyngeal Neoplasms/radiotherapy/*surgery Laryngeal Neoplasms/radiotherapy/*surgery Male Middle Aged Pharyngeal Neoplasms/*surgery Prognosis
Pubmed
Web of science
Create date
24/01/2008 18:12
Last modification date
20/08/2019 15:36
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