Cancer du sein de stade précoce : la désescalade thérapeutique sélective [Selective therapeutic de-escalation in early stage breast cancer]

Details

Serval ID
serval:BIB_7A29F888A008
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Cancer du sein de stade précoce : la désescalade thérapeutique sélective [Selective therapeutic de-escalation in early stage breast cancer]
Journal
Revue medicale suisse
Author(s)
Liapi A., Sarivalasis A., Jeanneret Sozzi W., Lelièvre L., Zaman K.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
17/05/2017
Peer-reviewed
Oui
Volume
13
Number
563
Pages
1035-1038
Language
french
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
The survival of patients with breast cancer has improved considerably thanks to adjuvant radiotherapy and systemic treatments. Due to the potential adverse events associated with these treatments, a de-escalation effort was undertaken concerning surgery and more recently the adjuvant treatments. Conservative breast surgery and the avoidance of axillary dissection were possible for the majority of the patients without detrimental effect on survival. New radiotherapy techniques and the consideration of cancer biology allowed to better protect the peripheral organs and even to avoid treatment in certain low-risk patients. The refinement of prognostic and predictive criteria helped reducing the use of chemotherapy and adapting the duration of endocrine therapy to the risk.
Keywords
Breast Neoplasms/diagnosis, Breast Neoplasms/pathology, Breast Neoplasms/therapy, Conservative Treatment/methods, Female, Humans, Medical Futility, Neoplasm Staging, Patient Selection, Prognosis
Pubmed
Create date
22/06/2017 21:16
Last modification date
31/10/2019 14:05
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