Systemic Diseases, Sepsis, Multiple Organ Dysfunction Syndrome

Details

Serval ID
serval:BIB_7963DFB01AB3
Type
A part of a book
Publication sub-type
Chapter: chapter ou part
Collection
Publications
Institution
Title
Systemic Diseases, Sepsis, Multiple Organ Dysfunction Syndrome
Title of the book
Atlas of Postmortem Angiography
Author(s)
Heinemann A., Grimm J.
Publisher
Springer International Publishing
ISBN
9783319285351
9783319285375
Publication state
Published
Issued date
2016
Chapter
22
Pages
285-294
Language
english
Abstract
The fatal outcome of polytrauma is frequently linked with trauma-associated infections that generalize to systemic inflammation, and with multiple organ dysfunction syndrome as a cause of death. Likewise, end-stage internal affliction such as metastasizing tumor disease is characterized by this type of systemic failure. Postmortem angiography is predominantly the means of choice for adding value to autopsy findings when neoplasms cause disturbed blood flow and fatal hemorrhages. The source of fatal bleeding is of particular interest in post-surgery fatalities following tumor resections. Mass-occupying lesions sometimes appear to displace adjacent vasculature in postmortem CT angiography (PMCTA), but postmortem contrast enhancement rarely facilitates the detection of small and medium-sized tumors. PMCTA may be particularly helpful in cases of large-vessel vasculitis, paraneoplastic thrombosis, septic embolism, or spontaneous hemorrhage in patients with coagulation disorder. Multiple organ dysfunction syndrome facilitates a general enhancement of organ tissues (particularly in liver, spleen, and kidney parenchyma) owing to the distribution of oil-based agents for postmortem angiography, as in multiphase PMCTA. However, prolonged postmortem periods may result in a similar phenomenon.
Keywords
Postmortem angiography Sepsis Neoplasm Multiple organ dysfunction syndrome Arteriovenous malformation
Create date
13/11/2017 14:59
Last modification date
20/08/2019 14:35
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