Prediction of postnatal outcome in fetuses with pulmonary hypoplasia by fetal-MRI: Comparison between lung volumetry and pulmonary signal intensity values

Details

Serval ID
serval:BIB_796192E6CFDD
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Title
Prediction of postnatal outcome in fetuses with pulmonary hypoplasia by fetal-MRI: Comparison between lung volumetry and pulmonary signal intensity values
Title of the conference
Swiss Radiological Congress 2010, Schweizerische Gesellschaft für Radiologie, Schweizerische Gesellschaft für Nuklearmedizin, Schweizerische Vereinigung der Fachleute für medizinisch technische Radiologie
Author(s)
Tenisch E., Senggen E., Meuli R., Gudinchet F., Alamo L.
Address
Lugano, Switzerland, June 3-5, 2010
ISBN
1424-4985
Publication state
Published
Issued date
2010
Volume
10
Series
Swiss Medical Forum = Forum Médical Suisse
Pages
11
Language
english
Abstract
Purpose: Pulmonary hypoplasia is a determinant parameter for
extra-uterine life. In the last years, MRI appears as a complement to US
in order to evaluate the degree of pulmonary hypoplasia in foetuses with
congenital anomalies, by using different methods - fetal lung volumetry
(FLV), lung-to-liver signal intensity ratio (LLSIR)-. But until now,
information about the correlation between the MRI prediction and the
real postnatal outcome is limited.
Methods and materials: We retrospectively reviewed the fetal MRI
performed at our Institution in the last 8 years and selected the cases
with suspicion of fetal pulmonary hypoplasia (n = 30). The pulmonary
volumetry data of these foetuses were collected and the lung-to-liver
signal intensity ratio (LLSIR) measures performed. These data were
compared with those obtained from a control group of 25 foetuses
considered as normal at MRI. The data of the study group were also
correlated with the autopsy records or the post-natal clinical information
of the patients.
Results: As expected, the control group showed higher FLV and LLSIR
values than the problem group at all gestational ages. Higher values of
FLV and LLSIR were associated with a better post-natal outcome.
Sensitivity, specificity, positive and negative predictive values and
accuracy for the relative LLSIR and the relative FLV showed no
significant differences.
Conclusion: Our data show that not only the FLV but also the relative
LLSIR inform about the degree of fetal lung development. This
information may help to predict the fetal outcome and to evaluate the
need for neonatal intensive care.
Create date
29/06/2010 16:05
Last modification date
03/03/2018 18:31
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