Magnetic resonance assessment of prevalence and correlates of right ventricular abnormalities in isolated left ventricular noncompaction.
Details
Serval ID
serval:BIB_78F05B7934FE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Magnetic resonance assessment of prevalence and correlates of right ventricular abnormalities in isolated left ventricular noncompaction.
Journal
The American journal of cardiology
ISSN
1879-1913 (Electronic)
ISSN-L
0002-9149
Publication state
Published
Issued date
01/01/2014
Peer-reviewed
Oui
Volume
113
Number
1
Pages
142-146
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The aim of the present study was to evaluate the prevalence and correlates of right ventricular (RV) noncompaction (RVNC), RV systolic dysfunction, and RV myocardial fibrosis in patients with isolated left ventricular (LV) noncompaction (LVNC). For this purpose, cine and contrast-enhanced cardiac magnetic resonance imaging (MRI) was used. A total of 56 consecutive patients with isolated LVNC were included in the study. The diagnosis of isolated LVNC was based on the presence of standard cardiac MRI and clinical criteria. For each patient, cine and contrast-enhanced cardiac MR images were analyzed to evaluate the prevalence and correlates of RVNC, RV dysfunction, and late gadolinium enhancement (a surrogate of myocardial fibrosis) involving the RV. Mean age of the patient population was 45 ± 19 years; 35 patients (63%) were men. RVNC was observed in 5 patients (9%). Impaired RV systolic function was observed in 9 patients (16%). Late gadolinium enhancement was not observed in any RV segment. No association was found between wall motion abnormalities and noncompaction at RV segmental level (φ coefficient 0.041, p = 0.26). At multivariate analysis, LV ejection fraction was the only variable independently related to RV ejection fraction (β = 0.62, p <0.001). In conclusion, RV systolic dysfunction is present in a non-negligible proportion of patients with isolated LVNC; LV systolic function is the only variable independently related to RV systolic function.
Keywords
Adult, Aged, Female, Follow-Up Studies, Heart Ventricles/abnormalities, Heart Ventricles/pathology, Humans, Isolated Noncompaction of the Ventricular Myocardium/diagnosis, Isolated Noncompaction of the Ventricular Myocardium/epidemiology, Magnetic Resonance Imaging, Cine/methods, Male, Middle Aged, Prognosis, Reproducibility of Results, United States/epidemiology, Ventricular Function, Right/physiology
Pubmed
Web of science
Create date
25/08/2017 21:40
Last modification date
20/08/2019 15:35