Activation macrophagique et Mycobacterium leprae: action de l'interféron gamma sur la production de radicaux oxygénés libres (R.O.L.) des cellules phagocytaires

Details

Serval ID
serval:BIB_7883B326A42E
Type
Article: article from journal or magazin.
Collection
Publications
Title
Activation macrophagique et Mycobacterium leprae: action de l'interféron gamma sur la production de radicaux oxygénés libres (R.O.L.) des cellules phagocytaires
Journal
Dakar Médical
Author(s)
Launois P., Dieye A., Blum L., Millan J., Sarthou J.L.
ISSN
0049-1101 (Print)
ISSN-L
0049-1101
Publication state
Published
Issued date
1989
Volume
34
Number
1-4
Pages
78-82
Language
french
Notes
[Macrophage activation and Mycobacterium leprae: effect of interferon gamma on the production of oxygen free radicals by phagocytic cells].
Abstract
Activation of the respiratory metabolic channel (F.O.R.), responsible in part for the bactericidal effect, was measured in vitro by a chemoluminescence test on circulating phagocytes. All mycobacteria tested, except for Mycobacterium leprae, induced a significant response. Its effect on lepromatous leprosy pathology is a subject for discussion.
Keywords
Free Radicals, Humans, Interferon-gamma/physiology, Luminescent Measurements, Macrophage Activation, Macrophages/metabolism, Mycobacterium/physiology, Mycobacterium leprae/physiology, Oxidation-Reduction, Oxygen/metabolism
Pubmed
Create date
28/01/2008 11:06
Last modification date
20/08/2019 14:35
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