Tumour-associated antigens in maternal and fetal blood

Details

Serval ID
serval:BIB_7863018C9BB1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Tumour-associated antigens in maternal and fetal blood
Journal
Prenatal Diagnosis
Author(s)
Hohlfeld  P., Dang  T. T., Nahoul  K., Daffos  F., Forestier  F.
ISSN
0197-3851 (Print)
Publication state
Published
Issued date
10/1994
Volume
14
Number
10
Pages
907-12
Notes
Comparative Study
Journal Article --- Old month value: Oct
Abstract
Normal levels of cancer-associated antigen (CA) 19-9, neurone-specific enolase (NSE), cancer-associated antigen (CA) 125, and mucin-like carcinoma-associated antigen (MCA) during pregnancy were determined in 87 mothers and fetuses, using a solid-phase sandwich enzyme immunoassay. CA 19-9 concentrations were higher in the fetuses, whereas the other three tumour-associated antigen levels were higher in the mothers. Only fetal NSE and MCA levels were positively correlated with those in maternal serum. Contrary to adult samples, no difference was demonstrated between male and female fetal levels of CA 125. MCA was the only maternal marker that increased significantly with gestational age between 20 and 34 weeks' pregnancy.
Keywords
Antigens, Tumor-Associated, Carbohydrate/*blood CA-125 Antigen/*blood CA-19-9 Antigen/*blood Female Fetal Blood/*immunology Gestational Age Humans Immunoenzyme Techniques Male Phosphopyruvate Hydratase/*blood Pregnancy Reference Values Tumor Markers, Biological/*blood
Pubmed
Web of science
Create date
25/01/2008 12:12
Last modification date
20/08/2019 15:35
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