Das Melanom in der Frauenheilkunde. [Melanoma in gynecology]

Details

Serval ID
serval:BIB_785BD76F8206
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Das Melanom in der Frauenheilkunde. [Melanoma in gynecology]
Journal
Geburtshilfe und Frauenheilkunde
Author(s)
Musfeld  D., De Grandi  P.
ISSN
0016-5751 (Print)
Publication state
Published
Issued date
12/1986
Volume
46
Number
12
Pages
857-62
Notes
English Abstract
Journal Article --- Old month value: Dec
Abstract
The malignant malignoma originates from the neutral tube and can be found in nearly every part of the body. Middle-aged women are most frequently affected. Histopathologically the melanoma can be subdivided into lentigo maligna melanoma, superficial spreading melanoma, nodular melanoma and non-classifiable melanoma. The histopathological classification as suggested by Clark and Breslow, completed by the "Prognosis-Index" of Schmoeckel and Braun-Falco, is of prognostic and therapeutic value. 3-5% of all melanomas are localised in the vulva at an average age of 60 years. The vagina is rarely affected, and, if so, at an earlier age. The tumour must be removed in total. Diagnostic biopsy is generally accepted, if followed by adequate therapy. Therapeutic possibilities are discussed. The influence exercised by pregnancy on the formation and evolution of a malignant melanoma is still controversial. Diaplacentar metastases are described. As long as the malignant melanoma remains limited to the upper chorium and the diameter does not exceed 1.5 mm, pregnancy can be tolerated with close supervision without influencing the further evolution of the tumour. Total excision should be performed regardless of the pregnancy stage.
Keywords
Female Humans Lymph Nodes/pathology Lymphatic Metastasis Melanoma/*pathology/therapy Prognosis Vagina/pathology Vaginal Neoplasms/*pathology/therapy Vulva/pathology Vulvar Neoplasms/*pathology/therapy
Pubmed
Web of science
Create date
25/01/2008 15:40
Last modification date
20/08/2019 14:35
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